diff --git a/gdb/configure.ac b/gdb/configure.ac
index 6f9a42c..2154574 100644
--- a/gdb/configure.ac
+++ b/gdb/configure.ac
@@ -734,7 +734,7 @@ if test "${with_python}" = no; then
   have_libpython=no
 else
   case "${with_python}" in
-  /*)
+  /* | [A-Za-z]:/* )
     if test -d ${with_python}; then
       # Assume the python binary is ${with_python}/bin/python.
       python_prog="${with_python}/bin/python"